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. 2017 Jun 15;24(1):932–941. doi: 10.1080/10717544.2017.1337823

Table 3.

Pharmacokinetic data of AT following single oral administration (25 mg/kg) of NLC-1, AT suspension and commercial tablet to rats.

Pharmacokinetic parameters NLC-1 AT suspension Lipitor®
Cmax (μg/ml) 25 ± 1.4a 9.7 ± 1.5 11.9 ± 1.3
Tmax (hr) 2 ± 0.25a 1.5 ± 0.15 1.5
AUC0–∞ (μgahr/ml) 599 ± 224.3a 168.1 ± 27 286.3 ± 38.5
AUC0–24 (μgahr/ml) 370.9 ± 65a 101.8 ± 2.7 129.3 ± 3.7
Relative bioavailability   3.56 2.09

Each value expressed as the mean ± SD (n = 3).

a

Significant at p < .05.