Table 3.
Pharmacokinetic parameters | NLC-1 | AT suspension | Lipitor® |
---|---|---|---|
Cmax (μg/ml) | 25 ± 1.4a | 9.7 ± 1.5 | 11.9 ± 1.3 |
Tmax (hr) | 2 ± 0.25a | 1.5 ± 0.15 | 1.5 |
AUC0–∞ (μgahr/ml) | 599 ± 224.3a | 168.1 ± 27 | 286.3 ± 38.5 |
AUC0–24 (μgahr/ml) | 370.9 ± 65a | 101.8 ± 2.7 | 129.3 ± 3.7 |
Relative bioavailability | 3.56 | 2.09 |
Each value expressed as the mean ± SD (n = 3).
Significant at p < .05.