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. 2017 Aug 28;24(1):1191–1203. doi: 10.1080/10717544.2017.1365395

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — (a) Flow cytometric images to detect apoptosis and (b) apoptosis percentage on A549 cells after applying yuanhuacine, yuanhuacine/PLGA-NPs, and yuanhuacine/MNPs with yuanhuacine concentration of 10 μM for 24 h. *p < .05, **p < .01 versus yuanhuacine, #p < .05 versus yuanhuacine/PLGA-NPs. (c) Cell cycle and (d) cell percentage in G2 phase on A549 cells after applying yuanhuacine, yuanhuacine/PLGA-NPs, and yuanhuacine/MNPs with yuanhuacine concentration of 10 μM for 24 h. *p < .05, **p < .01 versus control. (e) Mitochondrial membrane potential measurement and (f) cytochrome c detection on A549 cells after applying yuanhuacine, yuanhuacine/PLGA-NPs and yuanhuacine/MNPs at a yuanhuacin concentration of 10 μM for 24 h.