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. 2017 Feb 6;24(1):422–429. doi: 10.1080/10717544.2016.1259372

Table 5. Pharmacokinetic parameters of puerarin in mice brain after administration of NCS, ICS and SMEDDS containing both of puerarin (200 mg/kg) and borneol (100 mg/kg) (n = 6).

Parameters NCS SMEDDS ICS
AUC(0–12 h) (ng/mL × h) 1303.75 ± 387.47 2199.81 ± 328.98b 1488.09 ± 299.92c
t1/2 (h) 4.30 ± 1.63 5.71 ± 1.03 2.20 ± 0.49a,d
Tmax (h) 1.13 ± 0.60 0.85 ± 0.22 0.75 ± 0.18
Cmax (ng/mL) 220.25 ± 69.29 462.48 ± 55.75b 385.94 ± 84.61a

ap < 0.05 compared with NCS.

b

p < 0.01 compared with NCS.

c

p < 0.05 compared with SMEDDS.

d

p < 0.01 compared with SMEDDS.