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In vitro release studies. The GSH-sensitive release of PPM (A) and degradation of PPM-S-S-VE conjugate (C) from MPSSV-NP were studied at 37 °C under four different conditions, i.e. 10 mM, 1 mM, 10 μM, and 1 μM GSH, respectively (n = 3); in vitro cytotoxicity of PSSV-NPs and MPSSV-NPs with various concentration on MCF-7 (B) and HepG2 (D) cells after 72 h of incubation. (error bars are mean ± SD, n = 3).
