Table 3.
Symptoms and severity on admission, and maximal level of care received during admission, by age and respiratory condition
|
Patients aged 16–49 years |
Patients aged ≥50 years |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| No asthma (n=7083) | Asthma (n=1867) | p value | No respiratory condition (n=47 398) | Asthma (n=5918) | Chronic pulmonary disease (n=10 266) | Chronic pulmonary disease and asthma (n=2071) | p value | ||
| Symptoms on admission | |||||||||
| Fever | 5039 (71·1%) | 1325 (71·0%) | 0·93 | 25 864 (54·6%) | 3548 (60·0%) | 5150 (50·2%) | 1096 (52·9%) | <0·0001 | |
| Dyspnoea | 4501 (63·5%) | 1388 (74·3%) | <0·0001 | 26 479 (55·9%) | 4058 (68·6%) | 7108 (69·2%) | 1479 (71·4%) | <0·0001 | |
| Wheeze | 233 (3·3%) | 271 (14·5%) | <0·0001 | 1988 (4·2%) | 729 (12·3%) | 1305 (12·7%) | 374 (18·1%) | <0·0001 | |
| Cough | 4847 (68·4%) | 1427 (76·4%) | <0·0001 | 26 054 (55·0%) | 3965 (67·0%) | 6399 (62·3%) | 1387 (67·0%) | <0·0001 | |
| Severity on admission | |||||||||
| Days of symptoms before admission | |||||||||
| Median (IQR) | 6 (2–9) | 6 (2–9) | 0·22 | 2 (0–7) | 4 (0–8) | 2 (0–7) | 2 (0–7) | <0·0001 | |
| NEWS2 | |||||||||
| Median (IQR) | 4 (2–6) | 4 (2–6) | 0·00020 | 4 (1–6) | 4 (2–6) | 5 (3–6) | 4 (2–7) | <0·0001 | |
| 0–4 | 3495 (49·3%) | 846 (45·3%) | 0·00020 | 23 992 (50·6%) | 3026 (51·1%) | 4251 (41·4%) | 918 (44·3%) | <0·0001 | |
| 5–6 | 1219 (17·2%) | 410 (22·0%) | .. | 7270 (15·3%) | 1015 (17·2%) | 1989 (19·4%) | 421 (20·3%) | .. | |
| ≥7 | 1198 (16·9%) | 320 (17·1%) | .. | 8398 (17·7%) | 1043 (17·6%) | 2714 (26·4%) | 452 (21·8%) | .. | |
| Data missing | 1171 (16·5%) | 291 (15·6%) | .. | 7738 (16·3%) | 834 (14·1%) | 1312 (12·8%) | 280 (13·5%) | .. | |
| Outcomes | |||||||||
| Survival | |||||||||
| Alive | 6594 (93·1%) | 1714 (91·8%) | 0·063 | 30 600 (64·6%) | 4188 (70·8%) | 5873 (57·2%) | 1288 (62·2%) | <0·0001 | |
| Died | 382 (5·4%) | 122 (6·5%) | .. | 16 106 (34·0%) | 1670 (28·2%) | 4269 (41·6%) | 753 (36·4%) | .. | |
| Data missing | 107 (1·5%) | 31 (1·7%) | .. | 692 (1·5%) | 60 (1·0%) | 124 (1·2%) | 30 (1·4%) | .. | |
| Critical care | 1542 (22·0%) | 451 (24·5%) | 0·025 | 6135 (13·3%) | 1023 (17·5%) | 735 (7·2%) | 184 (9·0%) | <0·0001 | |
| Invasive mechanical ventilation | 953 (13·7%) | 269 (14·8%) | 0·24 | 3889 (8·6%) | 611 (10·6%) | 305 (3·0%) | 82 (4·1%) | <0·0001 | |
| Non-invasive ventilation | 1159 (16·7%) | 385 (21·2%) | <0·0001 | 6565 (14·5%) | 1086 (18·8%) | 1427 (14·3%) | 309 (15·4%) | <0·0001 | |
| Oxygen therapy | 3878 (55·6%) | 1099 (60·5%) | 0·00020 | 29 954 (65·9%) | 3991 (68·7%) | 7291 (72·5%) | 1392 (68·8%) | <0·0001 | |
| Median length of stay (IQR) | 3 (0–27) | 3 (0–29) | 0·50 | 6 (1–33) | 4 (1–31) | 6 (1–32) | 5 (1–30) | 0·0043 | |
| Median length of stay, survivors (IQR) | 3 (0–27) | 3 (0–29) | 0·42 | 5 (1–33) | 4 (1–32) | 5 (1–31) | 5 (1–29) | 0·039 | |
Data are n (%) or median (IQR). NEWS2=National Early Warning Score 2.