Table 1.

Specificity and Sensitivity of the 8 Polymorphisms in B.1.1.7 for Strain Identification

Polymorphisma	Strain				Specificity/Sensitivity, %e
	B.1.1.7b	B.1.1.28c	B.1.351d	WTd
H69/V70 deletion					98.73/100
WT	0	374	834	36 577
Del	26 328	0	0	470
Y144 deletion					99.87/100
WT	0	374	834	35 708
Del	26 328	0	0	46
N501Y					99.52/100
A	0	294	0	36 868
U	26 328	80	834	177
A570D					99.98/99.99
C	2	374	833	37 597
A	26 359	0	0	0
P681H					99.69/99.97
C	0	374	832	37 442
A	26 351	0	1	34
T716I					99.94/99.99
C	2	374	832	37 528
U	26 351	0	1	23
S982A					100/100
U	0	374	831	37 563
G	26 360	0	0	0
D1118H					99.98/99.97
G	0	374	834	37 579
C	26 358	0	0	8

Abbreviations: GISAID, Global Influenza Surveillance and Response System; SARS-CoV-2, severe acute respiratory syndrome coronavirus; WT, wild type.

^aSource UK. For each mutation, mutations associated with B.1.1.7 shown in lower row.

^bSource all. Available sequences from GISAID Nov, Dec 2020, and Jan 2021.

^cSource all. All available sequence worldwide.

^dSource UK. Available sequences from GISAID Jan-April, July, Nov, Dec 2020, and Jan 2021.

^eSpecificity and sensitivity for differentiation B.1.1.7 from WT SARS-CoV-2 sequences.