Table 3.
Correlations between OS and patient and tumor characteristics.
| Univariate analysis | P value | Multivariate analysis | P value | |||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | Hazard ratio | 95% CI | |||
| Age (>59 years) | 0.691 | 0.537–0.891 | 0.004 | 0.883 | 0.674–1.158 | 0.370 |
| Sex (male) | 1.090 | 0.836–1.420 | 0.525 | |||
| Body mass index (<18.5 or >25 kg/m2) | 1.168 | 0.879–1.552 | 0.285 | |||
| ECOG PS score (>1) | 0.951 | 0.671–1.349 | 0.780 | |||
| Pathological differentiation (poorly) | 1.409 | 1.062–1.868 | 0.017 | 1.268 | 0.952–1.688 | 0.105 |
| The number of organs affected by metastasis (>1) | 1.493 | 1.146–1.946 | 0.003 | 1.272 | 0.933–1.733 | 0.128 |
| Peritoneal metastasis (Yes) | 1.924 | 1.457–2.542 | <0.001 | 1.558 | 1.106–2.196 | 0.011 |
| TNM staging (IV) | 1.338 | 0.982–1.822 | 0.065 | 0.945 | 0.668–1.337 | 0.749 |
| CEA (>5 ng/mL) | 1.240 | 0.960–1.602 | 0.099 | 1.284 | 0.956–1.723 | 0.097 |
| CA19-9 (>37 U/mL) | 1.196 | 0.922–1.550 | 0.178 | 1.215 | 0.925–1.596 | 0.161 |
| CA72-4 (>6 U/mL) | 1.278 | 0.993–1.645 | 0.057 | 1.034 | 0.789–1.356 | 0.808 |
| Thrombocyte counts (>300 × 109/L) | 1.164 | 0.891–1.520 | 0.267 | |||
| ADR (≥41.64) | 0.273 | 0.202–0.369 | <0.001 | 0.317 | 0.231–0.437 | <0.001 |
ADR, albumin to D-dimer ratio; ECOG PS, Eastern Cooperative Oncology Group performance status; CEA, carcinoembryonic antigen; CA72-4, carbohydrate antigen 72-4; CA19-9, carbohydrate antigen 19-9; CI, confidence interval; OS, overall survival.