(a) Box plots of His34-Tyr453, Glu35-Gln493, Asp38-Tyr449 distances, and snapshots of residues and their distances at the last frame of simulation (200 ns) for the (b) control, (c) Nilotinib, and (d) SSAA09E2 cases. Distances are shown by dashed black lines. To see this figure in color, go online.