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. 2021 Jun 30;114:105131. doi: 10.1016/j.bioorg.2021.105131

Table 1.

Antiproliferative properties of the tested compounds.

Entry Compd. IC50 (μM) ± SE
PaCa-2 MCF7 HCT116
1 6a 8.30 ± 0.44 6.85 ± 0.37 16.38 ± 0.70
2 6b 5.60 ± 0.57 4.25 ± 0.23 12.77 ± 1.41
3 6c 4.99 ± 0.29 4.28 ± 0.51 5.33 ± 0.46
4 10a 6.91 ± 0.89 6.07 ± 0.83 20.96 ± 1.75
5 10b 5.08 ± 0.57 4.15 ± 0.78 13.83 ± 1.06
6 10c 6.18 ± 0.32 4.43 ± 0.47 >50.00 ± 0.84
7 Sunitinib 16.91 ± 0.95 3.97 ± 0.14 5.03 ± 0.30