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. 2021 Mar 30;28(7):3893–3900. doi: 10.1016/j.sjbs.2021.03.063

Table 2.

AChE and BuChE inhibitory activity of secondary metabolites tinosporide and 8-hydroxytinosporide obtained from T. cordifolia where donepezil was used as standard drug.

Tested compounds AChE inhibition
(IC50 (μg/ml) ± SEM)
BuChE inhibition
(IC50 (μg/ml) ± SEM)
Donepezil 6.31 ± 0.089 11.93 ± 0.129
Tinosporide 13.45 ± 0.144 408.50 ± 17.197
8-Hydroxytinosporide 46.71 ± 0.511 317.26 ± 6.918