Each value indicates the mean ± S.E.M. Statistical analysis was carried out by using unpaired t-test at level of significance P < 0.05. Fig. 5, FSH hormone level, Fig. 6, total testosterone hormone. In both figure, Pre-treated group received buffer intra-muscularly twice per week for 48 day, Post-treated group injected intra-muscular with 1 mg of Chondrus crispus with dose 0.1 ml/ twice per week for 48 day.