Table 1.
Comparison of three HO isozymes
| HO-1 | HO-2 | HO-3 | |
|---|---|---|---|
|
Molecular weight Inducibility Activity level |
32kD Stress-inducible High |
36kD Constitutive High |
Unknown Unknown Low |
| Highly-Expressed localization | Live, spleen, bone marrow, senescent erythrocytes | Brain, retina and testis | Widely distributed |
| Similarity | Degrade heme into biliverdin, carbon monoxide, ferrous ion and bilirubin | ||