Table 5.
The laboratory characteristics between mild COVID-19 patients and severe COVID-19 patients
| Biomarkers | Mild patients | Severe patients | P-value5 | TPR6 | TNR7 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Median1 | Min2, Max3 | Std. D4 | Median1 | Min2, Max3 | Std. D4 | ||||
| LYM cells (109) | 1.71 | (0.76, 2.47) | 0.53 | 0.68 | (0.26, 1.53) | 0.42 | 3.30E-06 | 0.23 | 0.80 |
| CD3+ (n/ul) | 1185.00 | (405.1, 1840) | 477.30 | 401.90 | (104.3, 922) | 281.30 | 2.90E-05 | 0.23 | 0.60 |
| NEUT (109/L) | 3.33 | (1.57, 5.34) | 0.94 | 6.01 | (1.85, 13.36) | 3.30 | 9.50E-05 | 0.13 | 0.25 |
| PLT (109/L) | 243.50 | (178, 398) | 50.87 | 151.50 | (73, 310) | 75.72 | 0.00029 | 0.21 | 0.16 |
| CD4+ (n/ul) | 637.50 | (235.6, 1270) | 343.90 | 270.30 | (52, 657.6) | 203.70 | 0.00030 | 0.38 | 0.43 |
| CD8+ (n/ul) | 379.20 | (142.9, 1032) | 222.10 | 127.50 | (44.72, 365) | 91.72 | 0.00036 | 0.15 | 0.65 |
| CRP (mg/L) | 5.00 | (<5, 50.7) | 10.79 | 19.97 | (5, 124.8) | 36.48 | 0.0008 | 0.15 | 0.13 |
| D dimer (mg/L) | 0.41 | (0.19, 1.02) | 0.21 | 1.64 | (0.26, 7.86) | 2.52 | 0.00212 | 0.13 | 0.12 |
| NK cells (n/ul) | 61.28 | (28.55, 278.9) | 55.33 | 19.49 | (7.74, 42.53) | 11.27 | 0.00257 | 0.15 | 0.15 |
| WBC (109/L) | 5.50 | (2.99, 8.38) | 1.33 | 7.53 | (2.96, 13.93) | 3.14 | 0.00412 | 0.13 | 0.22 |
| FDP (mg/L) | 1.60 | (0.9, 3.8) | 0.77 | 5.80 | (1.4, 34.1) | 10.36 | 0.00414 | 0.17 | 0.26 |
| TT (s) | 21.00 | (18.1, 23.2) | 1.25 | 20.15 | (17.4, 21) | 1.58 | 0.00470 | 0.13 | 0.14 |
| APTT (s) | 26.95 | (19.9, 33.3) | 3.90 | 31.00 | (23.4, 51.7) | 8.51 | 0.00662 | 0.21 | 0.21 |
| IL-10 (pg/ml) | 2.44 | (2.44, 8.72) | 1.39 | 4.71 | (2.44, 33.32) | 8.68 | 0.02014 | 0.15 | 0.58 |
| IL-6 (pg/ml) | 2.44 | (2.44, 58.1) | 14.11 | 15.91 | (2.44, 6040) | 2144.00 | 0.02591 | 0.38 | 0.05 |
| PDW (%) | 15.80 | (15.5, 16.5) | 0.33 | 16.20 | (15.2, 17.5) | 0.82 | 0.02705 | 0.13 | 0.12 |
| MCHC (pg) | 325.50 | (314, 341) | 7.22 | 318.00 | (283, 334) | 14.38 | 0.00044 | 0.00 | 0.07 |
| RDW-SD (%) | 37.00 | (31.9, 38.8) | 1.98 | 45.15 | (36.9, 84.4) | 14.01 | 0.00044 | 0.00 | 0.04 |
| PCT (%) | 0.21 | (0.15, 0.33) | 0.04 | 0.14 | (0.08, 0.31) | 0.07 | 0.00076 | 0.00 | 0.09 |
| INR | 0.96 | (0.84, 1.12) | 0.08 | 1.14 | (0.87, 1.74) | 0.22 | 0.00088 | 0.04 | 0.08 |
| PT (s) | 11.10 | (9.8, 13) | 0.98 | 13.15 | (10.1, 20.8) | 2.65 | 0.00109 | 0.04 | 0.05 |
| RBC (1012/L) | 4.20 | (3.02, 4.77) | 0.52 | 3.10 | (2.26, 5.16) | 0.83 | 0.00223 | 0.04 | 0.04 |
| Hb (g/L) | 118.50 | (92, 141) | 13.03 | 94.50 | (62, 150) | 24.39 | 0.00487 | 0.04 | 0.09 |
| ESR (mm/h) | 15.00 | (6, 102) | 22.48 | 57.00 | (6, 140) | 46.21 | 0.00510 | 0.00 | 0.04 |
| MCV (fl) | 91.30 | (76.6, 96.8) | 5.84 | 95.65 | (84.4, 114.5) | 8.99 | 0.00773 | 0.04 | 0.05 |
| Hct (%) | 37.00 | (26.9, 42.3) | 3.89 | 29.60 | (21.8, 47.1) | 6.91 | 0.01654 | 0.04 | 0.05 |
| RDW-CV (%) | 12.75 | (11.2, 15.3) | 1.08 | 13.95 | (12.7, 31.2) | 5.86 | 0.01668 | 0.04 | 0.17 |
| TNF-a (pg/ml) | 13.82 | (2.44, 138.6) | 41.48 | 4.85 | (2.44, 12.1) | 3.01 | 0.03608 | 0.00 | 0.20 |
1 Median: The intermediate value of each biomarker.
2 Min: The minimum value of each biomarker.
3 Max: The maximum value of each biomarker.
4 Std. D: The standard deviation of each biomarker.
5 P-value: P-value were calculated by Mann Whitney test.
6 TPR: The true positive rate.
7 TNR: The true negative rate.