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A. RNA expression levels for PAPP-A by RT-qPCR. B. Percentage of placental villi with positive protein expression for PAPP-A by using immunochemistry techniques. D-G. Images where immunoexpression of PAPP-A is showed in placental villi (D and F) and in decidual cells (E and G). CV D=Women with diagnosed gestational chronic venous disease. HC= Venous control p<0.05 (*), p<0.01 (**), and p<0.001 (***). Arrow=shows positive expression of the protein.
