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. 2021 Jun 29;11:13444. doi: 10.1038/s41598-021-92942-1

Table 1.

List of GO categories obtained after enrichment on gProfiler2 and linked to “immune response” and “interferon signaling” after a dose of 16.4 Gy proton therapy on CT26 tumors with an s-value < 0.005 and a Fold Change ≥ 2.

Id Term_id Term_name Intersection_size P_value
1 GO:0045087 Innate immune response 21 8.2e−11
2 GO:0002252 Immune effector process 19 5.1e−09
3 GO:0002376 Immune system process 31 7.0e−09
4 GO:0006955 Immune response 25 9.6e−09
5 GO:0034097 Respose to cytokine 18 3.2e−07
6 GO:0071345 Cellular response to cytokine stimulus 15 3.0e−05
7 GO:0035456 Response to interferon-beta 6 5.4e−05
8 GO:0035457 Cellular response to interferon-alpha 4 1.8e−04
9 GO:0035458 Cellular response to interferon-beta 5 7.0e−04
10 GO:0002682 Regulation of immune system process 17 7.9e−04
11 GO:0035455 Response to interferon-alpha 4 3.4e−03
12 GO:0032728 Positive regulation of interferon-beta production 4 5.1e−03
13 GO:0002218 Activation of initiate immune response 4 1.2e−02
14 GO:0032608 Interferon-beta production 4 3.0e−02
15 GO:0045088 Regulation of initiate immune response 6 3.4e−02
16 GO:0045089 Positive regulation of initiate immune response 5 3.7e−02