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. 2021 Jun 29;4:810. doi: 10.1038/s42003-021-02306-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A–E PCA plots of U-2 OS hyperLOPIT data⁹⁵, showing the top two principal components. Each pointer is a protein and marker proteins for each subcellular niche are coloured. Dark red diamonds denote proteins that were deemed to have non-sigmoid behaviour from TPP data. Each panel represents a different TPP dataset for the projected proteins. HyperLOPIT experiments are from biological triplicates with using a total of 57 fractions.