Table 5.
Unique amino acid substitutions shared between the Indian sub-continent lineage and Indonesian sequences (1974–1976).
| Polyprotein position | Gene | Gene position | REF | Cosmopolitan genotype | ||
|---|---|---|---|---|---|---|
| Indonesian (1974–1976; n = 07) | Indian sub-continent lineage (n = 94) | Other lineages (n = 344) | ||||
| 143 | preM | 29 | D | D (86%), N (14%) | D (100%) | N (100%) |
| 332 | E | 52 | Q | Q (71%), H (29%) | Q (100%) | H (97%) |
| 906 | NS1 | 131 | Q | Q (71%), H (29%) | Q (100%) | H (98%) |
| 1408 | NS2B | 63 | D | D (100%) | D (100%) | E (98%) |
| 1748 | NS3 | 273 | V | V (100%) | V (100%) | I (98%) |
| 1936 | NS3 | 461 | I | I (86%), V (14%) | I (98%) | V (97%) |
| 2589 | NS5 | 98 | R | R (71%), K (29%) | R (98%) | K (98%) |
| 3096 | NS5 | 605 | G | G (71%), V (29%) | G (100%) | V (98%) |
Percentage values indicate the extent of fixation of each mutation in respective groups of sequences. NCBI reference sequence NC_001474.2 was used as the reference (REF) genome. NS non-structural proteins, preM pre-membrane.