Table 6.
Time to most recent common ancestor (tMRCA) analysis of DENV-2 genotypes.
| Description | Node height (95% HPD) in years | Estimated year of emergencea |
|---|---|---|
| Root ancestor | 287.3 (164.8–440.3) | 1732 |
| Sylvatic | 140 (87.9–208.5) | 1879 |
| Cosmopolitan genotype | 64.5 (55–75.1) | 1955 |
| Cosmopolitan genotype (Indian sub-continent lineage) | 36.3 (30.6–41.9) | 1983 |
| Asian II genotype | 63.3 (49.1–77.6) | 1956 |
| Asian I genotype | 62 (56.5–68.5) | 1957 |
| American genotype | 65.3 (55.8–76.8) | 1954 |
| Asian-American genotype | 51.1 (43.8–60.1) | 1968 |
aEstimated year of emergence was calculated by subtracting the node height from 2019, which was the latest temporal data point in the analysis. The tMRCA data was obtained from the complete genome based maximum clade credibility tree. HPD Highest posterior density.