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. 2021 Jun 29;11:13459. doi: 10.1038/s41598-021-92958-7

Figure 5.

Figure 5

Centella extracts elevate transcription of antioxidant enzymes. (AD) CE promoted CAT expression, while APE enhanced SOD1 and SOD2 expression. BJ cells were incubated with CE (15–60 µg/mL; 24 h) or APE (60 µg/mL; 24 h) or H2O2 (200 µM; 1 h). The expressions of antioxidant machineries, including CAT, GPx1, SOD1, and SOD2, were determined with RT-PCR following treatments (n = 3; mean ± SEM; *P < 0.05 vs untreated control).