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. 2021 Jun 16;8:681669. doi: 10.3389/fmolb.2021.681669

TABLE 2.

The alteration of MDD diagnosis after the addition of pathological information.

Pre-biopsy dx Post-biopsy dx p value
UT-VATS (n = 67) TBLC (n = 70)
IPF (n = 13) IPF 8 IPF 3 0.40
RBILD/DIP 2
COP (n = 1) NA COP 1
RBILD/DIP (n = 7) RBILD/DIP 2 RBILD/DIP 2 0.15
IPF 2
HP 1
LIP (n = 2) NSIP 1 LIP 1
UIIP (n = 37) UIIP 9 UIIP 8 0.46
HP 4 IPF 3
IPF 3 NSIP 1
RBILD/DIP 2 Pneumoconiosis 1
IPAF 1 HP 1
LIP 1 ACIF 1
Vasculitis 1
ACIF 1
IPAF (n = 34) IPAF 12 IPAF 20 0.10
Sarcoidosis 1
HP 1
CTD-ILD (n = 22) CTD-ILD 9 CTD-ILD 12 0.43
IPF 1
HP (n = 3) IPAF 1 HP 1
Infection 1
Sarcoidosis (n = 1) Sarcoidosis 1 NA
PAP (n = 5) PAP 1 PAP 4
PLAM (n = 4) NA PLAM 4
Vasculitis (n = 1) Vasculitis 1 NA
Pneumoconiosis (n = 1) Lipid pneumonia 1
PLCH (n = 2) UIIP 1 PLCH 1
IPH (n = 1) NA IPH 1
PAM (n = 1) NA PAM 1
Infection (n = 1) NA Infection 1

UT-VATS: uniportal and tubeless-video-assisted thoracic surgery, TBLC: transbronchial lung cryobiopsy, IPF: idiopathic pulmonary fibrosis, NSIP: non-specific interstitial pneumonia, COP: cryptogenic organizing pneumonia, RB-ILD: respiratory bronchiolitis interstitial lung disease, DIP: desquamative interstitial pneumonia, LIP: lymphocyte interstitial pneumonia, ACIF: airway-lefted interstitial fibrosis, UIIP: undefined interstitial pneumonia, IPAF: interstitial pneumonia with autoimmune features, CTD-ILD: connective tissue disease-related ILD, HP: hypersensitivity pneumonitis, PAP: pulmonary alveolar proteinosis, PLAM: pulmonary lymphangioleiomyomatosis, PLCH: pulmonary Langerhans cell histiocytosis, IPH: idiopathic pulmonary hemosiderosis, PAM: pulmonary alveolar microlithiasis.