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. 2021 Jun 16;8:681669. doi: 10.3389/fmolb.2021.681669

TABLE 4.

The stratification of pathological information with different biopsy methods

UT-VATS TBLC p value
Total, n 67 70 0.02
Grade 1 23 (34.3) 9 (12.9) 0.003
Grade 2 33 (49.3) 41 (58.6) 0.27
Grade 3 5 (7.5) 6 (8.6) 0.81
Grade 4 6 (9.0) 14 (20.0) 0.06
Initial dx UIIP, n 22 15 0.27
Grade 1 13 (59.1) 7 (46.7) 0.46
Grade 2 1 (4.5) 0 (0) 0.40
Grade 3 5 (22.7) 2 (13.3) 0.47
Grade 4 3 (13.6) 6 (40.0) 0.06
Initial dx IPAF/CTD-ILD, n 23 33 0.14
Grade 1 2 (8.7) 0 (0) 0.08
Grade 2 19 (82.6) 25 (75.8) 0.54
Grade 3 0 (0) 3 (9.1) 0.14
Grade 4 2 (8.7) 5 (15.2) 0.47

Values are presented as number (%) unless specified. UT-VATS: uniportal and tubeless-video-assisted thoracic surgery, TBLC: transbronchial lung cryobiopsy, UIIP: undefined interstitial pneumonia, IPAF: interstitial pneumonia with autoimmune features, CTD-ILD: connective tissue disease-related interstitial lung disease. Grade 1: specific diagnosis with final diagnosis altered; grade 2: specific diagnosis without final diagnosis altered; grade 3: non-specific diagnosis with supplementary information provided; grade 4: non-informative diagnosis.