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Hematoxylin/eosin and Van Gieson staining of wound tissues on postoperative day 7(A) and 14 (B). The representative images show the wounds treated with ATP-vesicles have more intense collagen fibers (red color) than the wounds treated with neutral cream. The collagen fibers also exhibit a more organized pattern in ATP-vesicle-treated wounds on postoperative day 14. The arrows indicate positive staining of the collagen fibers. Scale bar is 50 μm.
