FIGURE 6.

A representative comparison of wound collagen by picrosirius red staining 7 days after surgery between the two groups. (A). Under a regular light microscope, ATP- vesicle-treated wounds show some large sized and regimented collagen fibrils (bright red), whereas the control wound has less and poorly-organized collagen. (B). Under circular polarized microscope, the study wound shows higher type I collagen contents (stained yellow and orange) while the control wound has fewer and mostly type III collagen (stained green). Scale bar is 50 μm.