Table 7.
Effects of dietary XOS supplementation on colon mRNA levels related to epithelial cell barrier function and inflammation in weaned piglets (n = 6).
| Items | Blank control group | XOS-supplemented groups (g/t) | Positive control group | Pooled SEM | P-value | ||
|---|---|---|---|---|---|---|---|
| 100 | 250 | 500 | |||||
| Occludin | 1.00 | 0.87 | 1.32 | 0.77 | 1.51 | 0.25 | 0.31 |
| Claudin 2 | 1.00ab | 0.87b | 1.55ab | 1.28ab | 1.79a | 0.24 | 0.02 |
| Claudin 3 | 1.00 | 0.81 | 1.27 | 0.72 | 0.83 | 0.26 | 0.62 |
| ZO-1 | 1.00b | 1.37ab | 1.90a | 1.47ab | 1.61ab | 0.22 | 0.03 |
| IL-1β | 1.00 | 1.16 | 1.65 | 1.35 | 1.10 | 0.20 | 0.11 |
| IL-8 | 1.00 | 1.04 | 1.29 | 1.24 | 0.90 | 0.23 | 0.16 |
| IL-10 | 1.00 | 1.22 | 1.26 | 1.16 | 1.10 | 0.34 | 0.67 |
Data in the same row with different superscripts differ significantly (P < 0.05). IL, interleukin; ZO-1, zonula occludens-1; β, beta.