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. 2021 Mar 31;12(3):345–355. doi: 10.1007/s12687-021-00516-5

Table 4.

Prevalence of the 36 specific anomalies selected according to health subsector and adjusted risk by the hospital (ad PRR) of being born in PUB hospital (public: PUB, or private/social security: PRI), RENAC 2010–2018

Specifically selected anomalies (ICD-10) N and prevalence × 10.000 (CI 95%) ad PRR PUB (IC95%) Specific selected anomalies (ICD-10) N and prevalence × 10.000 (CI 95%) ad PRR PUB
(IC95%)
PRI PUB PRI PUB
Anencephaly (Q00)

21

1.02

(0.63–1.55)

565

2.83

(2.60–3.07)

2.80 *

(1.71–4.58)

Transverse limb reduction defect (Q71.2–Q71.30)

27

1.31

(0.86–1.90)

345

1.73

(1.56–1.92)

1.32

(0.88–2.01)

Encephalocele (Q01)

11

0.53

(0.27–0.95)

264

1.32

(1.17–1.49)

2.50 *

(1.10–5.65)

Equinovarus Talipes (Q66.0)

71

3.43

(2.68–4.33)

1389

6.96

(6.60–7.33)

2.04 *

(1.30–3.19)

Spina bifida (Q05)

104

5.03

(4.11–6.09)

1118

5.60

(5.28–5.94)

1.12

(0.57–2.18)

Calcaneovalgus Talipes (Q66.4)

6

0.29

(0.11–0.63)

188

0.94

(0.81–1.09)

3.26*

(1.17–9.09)

Hydrocephaly (Q03)

98

4.74

(3.85–5.77)

1512

7.58

(7.20–7.97)

1.61 *

(1.14–2.27)

Esophageal atresia (Q39.0Q39.11)

62

3.00

(2.30–3.84)

672

3.37

(3.12–3.63)

1.13

(0.83–1.54)

Holoprosencephaly (Q04.1-04.2)

14

0.68

(0.37–1.14)

495

2.48

(2.27–2.71)

3.68 *

(2.06–6.56)

Intestinal atresia (Q41.1Q41.9)

26

1.26

(0.82–1.84)

338

1.69

(1.52–1.88)

1.35

(0.91–2.09)

Microcephaly (Q02)

25

1.21

(0.78–1.78)

499

2.50

(2.29–2.73)

2.08 *

(1.36–3.16)

Duodenal atresia (Q41.0)

44

2.13

(1.55–2.86)

337

1.69

(1.51–1.88)

0.80

(0.55–1.15)

Microphthalmia / anophthalmia (Q11.1-11.2)

24

1.16

(0.74–1.73)

271

1.36

(1.20–1.53)

1.18

(0.78–1.77)

Anorectal malformation (Q42.0Q42.3)

84

4.06

(3.24–5.03)

976

4.89

(4.59–5.21)

1.21

(0.92–1.60)

Anotia + microtia (Q16; Q17.1)

37

1.79

(1.26–2.47)

596

2.99

(2.75–3.24)

1.61 *

(1.02–2.56)

Diaphragmatic hernia (Q79.0Q79.01)

73

3.53

(2.77–4.44)

747

3.74

(3.48–4.02)

1.06

(0.51–2.24)

Cleft Palate (Q35)

63

3.05

(2.34–3.90)

426

2.13

(1.94–2.35)

1.03

(0.79–1.36)

Gastroschisis (Q79.3)

76

3.67

(2.90–4.60)

1657

8.30

(7.91–8.71)

2.27 *

(1.50–3.44)

Cleft Lip (Q36; exclude Q36.1, medial)

32

1.55

(1.06–2.18)

412

2.01

(1.87–2.27)

1.34

(0.93–1.92)

Omphalocele (Q79.2)

38

1.84

(1.30–2.52)

432

2.16

(1.97–2.38)

1.18

(0.79–1.77)

Cleft lip and palate (Q37)

138

6.67

(5.60–7.88)

2099

10.5

(10.1–11.0)

1.58 *

(1.24–2.03)

Bilateral Cryptorchidism (Q53.2)

26

1.26

(0.82–1.84)

220

1.10

(0.96–1.26)

0.88

(0.47–1.64)

Coarctation of the Aorta (Q25.1-Q25.19)

57

2.76

(2.09–3.57)

360

1.80

(1.62–2.00)

0.66 *

(0.47–0.92)

Ambiguous genitalia (Q56.4)

24

1.16

(0.74–1.73)

319

1.60

(1.43–1.78)

1.38

(0.97–1.96)

Hypoplasic left heart (Q23.4)

60

2.90

(2.21–3.73)

342

1.71

(1.54–1.91)

0.59 *

(0.45–0.79)

Hypospadias (Q54.1Q54.3)

86

4.16

(3.33–5.13)

496

2.49

(2.27–2.71)

0.60 *

(0.40–0.91)

Tetralogy of Fallot (Q21.3-Q21.87)

66

3.19

(2.47–4.06)

369

1.85

(1.67–2.05)

0.58 *

(0.40–0.83)

Bilateral renal agenesis (Q60.1)

10

0.83

(0.23–0.89)

174

0.87

(0.74–1.01)

1.81

(0.87–3.79)

Transposition of the great vessels (Q20.3)

63

3.05

(2.34–3.40)

365

1.83

(1.65–2.03)

0.60 *

(0.38–0.95)

Renal cysts (Q61.1Q61.90)

65

3.14

(2.43–4.01)

818

4.10

(3.82–4.39)

1.31

(0.90–1.90)

Double inlet left ventricle (Q20.4)

21

1.02

(0.63–1.55)

240

1.20

(1.06–1.36)

1.19

(0.72–1.95)

Down syndrome (Q90.090.9)

422

20.4

(18.5–22.4)

3391

17.0

(16.4–17.6)

0.83 *

(0.71–0.98)

Preaxial polydactyly (Q69.00; Q69.1; Q69.20)

22

1.06

(0.67–1.61)

300

1.50

(1.34–1.68)

1.42

(0.88–2.30)

Edwards

syndrome (Q91.0)

53

2.56

(1.92–3.35)

227

1.14

(0.99–1.30)

0.45 *

(0.28–0.70)

Postaxial polydactyly (Q69.02; Q69.22)

52

2.51

(1.88–3.30)

1056

5.29

(4.98–5.62)

2.11 *

(1.23–3.61)

Patau

syndrome (Q91.4)

18

0.87

(0.21–1.38)

88

0.44

(0.35–0.54)

0.51 *

(0.29–0.89)

PRR prevalence rate ratio of being born in PUB hospital

*Statistically significant