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. 2021 Mar 5;12(3):357–376. doi: 10.1007/s12687-021-00513-8

Table 10.

Comparison of estimated under-5 deaths per 1000 in South Africa 2012 for congenital anomalies, Global Burden of Disease (GBD) (Global Burden of Disease Collaborative Network 2018), Vital Registration (VR) data (Statistics South Africa 2012) and MGBb-ZA

2012 source Under-5 deaths/1000
Down Unbal chrom NTD OFC CHD Other CM Total chrom Total cong malfns Total cong anomalies
SA VR Data 0.13 0.11 0.10 0.02 0.48 0.88 0.24 1.47 1.71
GBD 2017 0.12 0.09 0.14 0.01 0.55 0.90 0.21 1.61 1.82
MGDb-ZA 0.69 0.54 0.48 0.12 1.72 4.78 1.23 7.09 8.32
VR % of MGDB-ZA 18% 20% 20% 14% 28% 18% 19% 21% 21%
GBD % of MGDb-ZA 17% 17% 30% 11% 32% 19% 17% 23% 22%