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. 2021 Jun 29;11:13519. doi: 10.1038/s41598-021-92977-4

Table 2.

Effect of Nigella sativa L. seed on serum luteinizing hormone, testosterone and oxidative stress parameters of rats suffer from monosodium glutamate-induced testicular dysfunction.

Group Control MSG MSG + NSS P value
Parameter
LH level (mU/ml) 16.167 ± 2.218b 37.733 ± 2.270a 21.800 ± 2.590b 0.002
Testosterone level (ng/ml) 2.600 ± 0.116a 1.650 ± 0.144b 2.400 ± 0.252a 0.022
LPO level (nmol/mL) 1.161 ± 0.139b 2.260 ± 0.130a 1.079 ± 0.165b 0.000
NO level (nmol/mL) 99.603 ± 5.541a 52.565 ± 4.769b 70.308 ± 7.097b 0.001
SOD activity (U/mL) 73.643 ± 2.081a 62.984 ± 2.340b 58.462 ± 4.130b 0.011
GST activity (U/L) 16.633 ± 1.637b 37.020 ± 3.298a 30.750 ± 3.031a 0.005
TAC (mM/L) 0.544 ± 0.046b 0.996 ± 0.135a 0.620 ± 0.038b 0.017

MSG monosodium glutamate, NSS Nigella sativa L. seed, LH luteinizing hormone, LPO lipid peroxides, NO nitric oxide, SOD superoxide dismutase, GST glutathione-S-transferase, TAC total antioxidant capacity.

Results are expressed as the mean ± SEM of 6 rats per group.

a,bDifferent letters indicate significant differences at P < 0.05 (one-way ANOVA followed by Duncan’s posthoc-test).