Table 4.

Comparing the s-AP3D1-Ab levels between HDs and patients with chronic kidney disease (CKD).

Numbers for the total samples, samples from male and female participants and ages (average ± SD)
Sample information	HD	Type-1 CKD	Type-2 CKD	Type-3 CKD
Total sample number	82	145	32	123
Male/Female	44/38	106/39	21/11	70/53
Age, years (average ± SD)	44.10 ± 11.19	66.04 ± 10.38	76.03 ± 9.78	61.98 ± 11.69

Serum AP3D1 antibody levels (s-AP3D1-Ab) examined by AlphaLISA
Patient group	Type of value	s-AP3D1-Ab
HD	Average	64,142
	SD	28,679
	Cutoff values	121,499
	Positive No	4
	Positive (%)	4.90%
Type-1 CKD	Average	104,416
	SD	43,875
	Positive No	40
	Positive (%)	27.60%
	P value (vs. HD)	< 0.001
Type-2 CKD	Average	114,921
	SD	38,248
	Positive No	12
	Positive (%)	37.50%
	P value (vs. HD)	< 0.001
Type-3 CKD	Average	93,285
	SD	38,419
	Positive No	28
	Positive (%)	22.80%
	P value (vs. HD)	< 0.001

The numbers shown are as described in Table 1. CKD was divided into three groups as follows: type 1, diabetic kidney disease; type 2, nephrosclerosis; and type 3, glomerulonephritis. P values of < 0.05 and positive rates of > 10% are marked in bold font. The plots for these data are shown in Fig. 4a.