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. 2021 Jun 29;11:13450. doi: 10.1038/s41598-021-92786-9

Table 5.

Comparing the serum anti-AP3D1 antibody levels of HDs versus those of patients with esophageal squamous cell carcinoma (ESCC) and colorectal carcinoma (CRC).

Patient group Type of value s-AP3D1-Ab
HD Average 15,169
SD 7065
Cutoff values 29,299
Total No 64
Positive No 2
Positive (%) 3.10%
ESCC Average 29,537
SD 13,468
Total No 64
Positive No 27
Positive (%) 42.20%
P value (vs. HD)  < 0.001
CRC Average 20,639
SD 8,659
Total No 64
Positive No 10
Positive (%) 15.60%
P value (vs. HD)  < 0.001

The s-AP3D1-Ab levels examined using AlphaLISA in HDs and patients with ESCC and CRC are shown. Purified AP3D1-GST proteins were used as antigens. The numbers shown are as described in Table 1. P-values of < 0.05 and positive rates of > 10% are marked in bold font. The plots for these data are shown in Fig. 5a.