Table 2.

Model performance using a selection of combinations of the six input data modalities.

Included data modalities						Ctd (95% CI)	IBS (95% CI)
Clinical	mRNA	DNAm	miRNA	CNV	WSI
$\bullet$	$\bullet$					0.822 (0.805–0.837)	0.138 (0.126–0.150)
$\bullet$		$\bullet$				0.808 (0.791–0.826)	0.134 (0.125–0.148)
$\bullet$			$\bullet$			0.792 (0.775–0.810)	0.147 (0.136–0.161)
$\bullet$				$\bullet$		0.795 (0.778–0.812)	0.140 (0.131–0.152)
$\bullet$					$\bullet$	0.801 (0.783–0.817)	0.148 (0.140–0.158)
$\bullet$	$\bullet$	$\bullet$				0.810 (0.793–0.829)	0.146 (0.135–0.158)
$\bullet$	$\bullet$	$\bullet$	$\bullet$			0.798 (0.781–0.815)	0.153 (0.139–0.168)
$\bullet$	$\bullet$	$\bullet$	$\bullet$	$\bullet$		0.802 (0.748–0.820)	0.149 (0.136–0.162)
$\bullet$	$\bullet$	$\bullet$	$\bullet$	$\bullet$	$\bullet$	0.787 (0.769–0.806)	0.152 (0.140–0.166)

Clinical tabular clinical data, mRNA gene expression, DNAm DNA methylation, miRNA microRNA expression, CNV gene copy number variation, WSI whole-slide images.

Individual data modalities included in each evaluated model are marked with $\bullet$. The best and second best results for each metric are boldfaced and italics, respectively.