Table 1.
Characteristic | IC + CRT group (n = 55), % | CRT group (n = 55), % |
---|---|---|
Age (years) | ||
Median (IQR) | 57 (52–62) | 60 (54–65) |
≤58 | 31 (56.4) | 25 (45.5) |
>58 | 24 (43.6) | 30 (54.5) |
Sex | ||
Male | 39 (70.9) | 43 (78.2) |
Female | 16 (29.1) | 12 (21.8) |
Smoking history | ||
Yes | 40 (72.7) | 41 (74.5) |
No | 15 (27.3) | 14 (25.5) |
Alcohol history | ||
Yes | 32 (58.2) | 36 (65.5) |
No | 23 (41.8) | 19 (34.5) |
Weight loss within 3 months | ||
<10% | 44 (80.0) | 43 (78.2) |
≥10% | 11 (20.0) | 12 (21.8) |
BMI (kg/m2) | ||
Median (IQR) | 21.6 (19.9–23.3) | 20.3 (18.6–22.0) |
≤18.5 | 5 (9.1) | 12 (21.8) |
>18.5 | 50 (90.9) | 43 (78.2) |
ECOG performance status | ||
0 | 28 (50.9) | 21 (38.2) |
1–2 | 27 (49.1) | 34 (61.8) |
Histologic grade | ||
Gx/G1/G2 | 47 (85.5) | 49 (89.1) |
G3 | 8 (14.5) | 6 (10.9) |
Tumor location | ||
Upper | 32 (58.2) | 26 (47.3) |
Middle | 20 (36.4) | 23 (41.8) |
Distal | 3 (5.5) | 6 (10.9) |
Primary tumor length (cm) | ||
Median (IQR) | 5 (4–7) | 5 (4–7) |
≤5 | 23 (41.8) | 27 (49.1) |
>5 | 32 (58.2) | 28 (50.9) |
Clinical T stage | ||
T1–2 | 16 (29.1) | 15 (27.3) |
T3–4 | 39 (70.9) | 40 (72.7) |
Clinical N stage | ||
N0 | 7 (12.7) | 9 (16.4) |
N1 | 48 (87.3) | 46 (83.6) |
Clinical M stage | ||
M0 | 40 (72.7) | 36 (65.5) |
M1a | 15 (27.3) | 19 (34.5) |
Clinical TNM stage | ||
IIA | 7 (12.7) | 8 (14.5) |
IIB | 8 (14.5) | 9 (16.4) |
III | 25 (45.5) | 19 (34.5) |
IVA | 15 (27.3) | 19 (34.5) |
Reason for no surgery | ||
Inoperable | 40 (72.7) | 38 (69.1) |
Surgical contraindication | 9 (16.4) | 11 (20.0) |
Patient refusal | 6 (10.9) | 5 (9.1) |
Radiotherapy modality | ||
3DCRT | 2 (3.6) | 4 (7.3) |
IMRT | 53 (96.4) | 51 (92.7) |
IC induction chemotherapy, CRT chemoradiotherapy, IQR interquartile range, BMI body mass index, ECOG Eastern Cooperative Oncology Group, 3DCRT three-dimensional conformal radiotherapy, IMRT intensity-modulated radiotherapy.