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. 2021 Jun 29;12:4014. doi: 10.1038/s41467-021-24288-1

Table 1.

Patient characteristics.

Characteristic IC + CRT group (n = 55), % CRT group (n = 55), %
Age (years)
 Median (IQR) 57 (52–62) 60 (54–65)
  ≤58 31 (56.4) 25 (45.5)
  >58 24 (43.6) 30 (54.5)
Sex
  Male 39 (70.9) 43 (78.2)
  Female 16 (29.1) 12 (21.8)
Smoking history
  Yes 40 (72.7) 41 (74.5)
  No 15 (27.3) 14 (25.5)
Alcohol history
  Yes 32 (58.2) 36 (65.5)
  No 23 (41.8) 19 (34.5)
Weight loss within 3 months
  <10% 44 (80.0) 43 (78.2)
  ≥10% 11 (20.0) 12 (21.8)
BMI (kg/m2)
  Median (IQR) 21.6 (19.9–23.3) 20.3 (18.6–22.0)
  ≤18.5 5 (9.1) 12 (21.8)
  >18.5 50 (90.9) 43 (78.2)
ECOG performance status
  0 28 (50.9) 21 (38.2)
  1–2 27 (49.1) 34 (61.8)
Histologic grade
  Gx/G1/G2 47 (85.5) 49 (89.1)
  G3 8 (14.5) 6 (10.9)
Tumor location
  Upper 32 (58.2) 26 (47.3)
  Middle 20 (36.4) 23 (41.8)
  Distal 3 (5.5) 6 (10.9)
Primary tumor length (cm)
  Median (IQR) 5 (4–7) 5 (4–7)
  ≤5 23 (41.8) 27 (49.1)
  >5 32 (58.2) 28 (50.9)
Clinical T stage
  T1–2 16 (29.1) 15 (27.3)
  T3–4 39 (70.9) 40 (72.7)
Clinical N stage
  N0 7 (12.7) 9 (16.4)
  N1 48 (87.3) 46 (83.6)
Clinical M stage
  M0 40 (72.7) 36 (65.5)
  M1a 15 (27.3) 19 (34.5)
Clinical TNM stage
  IIA 7 (12.7) 8 (14.5)
  IIB 8 (14.5) 9 (16.4)
  III 25 (45.5) 19 (34.5)
  IVA 15 (27.3) 19 (34.5)
Reason for no surgery
  Inoperable 40 (72.7) 38 (69.1)
  Surgical contraindication 9 (16.4) 11 (20.0)
  Patient refusal 6 (10.9) 5 (9.1)
Radiotherapy modality
  3DCRT 2 (3.6) 4 (7.3)
  IMRT 53 (96.4) 51 (92.7)

IC induction chemotherapy, CRT chemoradiotherapy, IQR interquartile range, BMI body mass index, ECOG Eastern Cooperative Oncology Group, 3DCRT three-dimensional conformal radiotherapy, IMRT intensity-modulated radiotherapy.