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. 2021 Jun 16;12:687546. doi: 10.3389/fpsyt.2021.687546

Table 1.

Sample characteristics of the total sample, and regular vs. occasional vs. never users of psychedelic substances in the past.

Total (N = 2,974) Regular users (N = 497) Occasional users (N = 606) Never users (N = 1,868) pa
Sociodemographics, N (%)
Age [years, mean (SD)] 36.3 (13.3) 40.0 (11.0) 38.5 (12.0) 34.7 (14.1) <0.001
Gender <0.001
   Men 852 (28.6) 247 (49.8) 202 (33.7) 403 (21.7)
   Women 2,087 (70.2) 248 (50.0) 392 (65.3) 1,447 (77.8)
   Queer/androgynous/others 18 (0.6) 1 (0.2) 6 (1.0) 11 (0.6)
Language questionnaire <0.001
   English 673 (22.6) 223 (44.9) 205 (33.8) 243 (13.0)
   Portuguese 689 (23.2) 47 (9.5) 70 (11.6) 572 (30.6)
   Spanish 1,613 (54.2) 227 (45.7) 331 (54.6) 1,053 (56.4)
Partner status 1,565 (52.6) 268 (54.0) 322 (53.2) 974 (52.2) 0.74
Religion and spirituality, N (%)
Religion groups <0.001
   Atheist 845 (28.4) 96 (21.8) 185 (33.8) 564 (30.8)
   Agnostic 695 (23.4) 164 (37.3) 194 (35.4) 337 (18.4)
   Religious 1,280 (43.0) 180 (40.9) 169 (30.8) 930 (50.8)
Practitioner of religion 931 (31.3) 186 (42.7) 176 (33.5) 569 (34.5) 0.003
Spiritual person 1,948 (65.5) 435 (87.5) 451 (74.4) 1,062 (56.9) <0.001
Spiritual practices 1,686 (56.7) 404 (81.3) 397 (65.5) 885 (47.4) <0.001
Health factors, N (%)
Chronic diseases 736 (24.7) 115 (23.1) 150 (24.8) 471 (25.2) 0.63
Mental diseases 670 (22.5) 96 (19.3) 153 (25.2) 421 (22.5) 0.06
Substance use, N (%)
Non-psychedelic
Alcohol 1,684 (56.6) 330 (66.4) 403 (66.5) 950 (50.9) <0.001
Tobacco 681 (22.9) 155 (31.2) 206 (34.0) 320 (17.1) <0.001
Cannabis 1,212 (40.7) 345 (69.4) 438 (72.5) 429 (23.0) <0.001
Cocaine 331 (11.1) 119 (23.9) 174 (28.7) 38 (2.0) <0.001
Amphetamines 266 (8.9) 113 (22.7) 132 (21.8) 21 (1.1) <0.001
Psychedelic
MDMA, ecstasy, mollyb 701 (23.6) 303 (61.0) 325 (53.6) 73 (3.9) <0.001
Ayahuasca 609 (20.5) 357 (71.8) 252 (41.6) 0 <0.001
Magic mushroom 841 (28.3) 418 (84.1) 423 (69.8) 0 <0.001
LSD 737 (24.8) 354 (71.2) 383 (63.2) 0 <0.001
Other psychedelics 487 (16.4) 296 (59.6) 191 (31.5) 0 <0.001
Context of use of psychedelic substances <0.001
   Not using anything 1,899 (63.8) 6 (1.8) 25 (5.6) 1,868 (100)
   Alone 65 (2.2) 42 (12.9) 23 (5.2) 0
   With friends or partner 293 (9.8) 91 (28.0) 202 (45.5) 0
   At parties or festivals 60 (2.0) 8 (2.5) 52 (11.7) 0
   Rituals/therapeutic 315 (10.6) 174 (53.5) 141 (31.8) 0
   Microdosing 5 (0.2) 4 (1.2) 1 (0.2) 0
a

Chi square tests for categorical variables and independent sample T-test for continuous variable;

b

Is only determined as a psychedelic drug when used for rituals or therapeutic settings. Significant (Bonferroni-corrected) p <0.002 are represented bold.