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. 2021 Jun 16;11:665484. doi: 10.3389/fonc.2021.665484

Table 3.

The characteristics of EGFR mutant patients harboring other potentially actionable drivers treated with first-generation EGFR TKIs.

Characteristics
Total number of patients 17
Median age (range) 60 (35–72)
Gender N, (%)
 Male 3 (18)
 Female 14 (82)
Smoking N, (%)
 Non-smoker 14 (82)
 Smoker 3 (18)
Pathology N, (%)
 ADC 15 (88)
 Non-ADC 2 (12)
EGFR mutation type N, (%)
 21L858R 12 (71)
 19del 4 (23)
 18G719A 1 (6)
Concomitant alterations N, (%)
 MET amplification  5 (29)
 ERBB2 amplification 5 (29)
 ERBB2 mutations 3 (18)
 MET exon 14 splicing mutation 1 (6)
 RET rearrangement 1 (6)
 NTRK rearrangement 1 (6)
 KRAS G12C mutation 1 (6)

ADC, adenocarcinoma.