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. 2021 Jun 16;12:666790. doi: 10.3389/fphar.2021.666790

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Copyright © 2021 Yu, Yao, Zhang, Ruan, Zhang, Xu, Liang and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BBB permeability evaluation of MCAO rats. (A) Representative brain pictures after the injection of Evans blue. (B) The contents of Evans blue in the brains of MCAO rats (n = 6). ^## p < 0.01 compared to the sham group; ^* p < 0.05, ^** p < 0.01 compared to the model group; ^&& p < 0.01 compared to the LCH + BO group.