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Chondro-protective effects of nanoparticles on IL-1β-induced chondrocytes. (a, b) qRT-PCR was performed to detect the expression levels of chondrogenic markers Col2α1 and Acan. (c) Quantification of GAG content. (d) Safranin O stained for GAG production (scale bar, 400 µm). Data were represented as the mean ± SD of three independent culture experiments (n = 3). #P < 0.05; ##P < 0.01; ***, ###P < 0.001.
