Figure 3.

Tanglegram of rodent hosts and their hepaciviruses. The topology of the host tree was reconstructed using the cytochrome b gene from twenty-one rodent species (left phylogeny). For the viral reconstruction we used the rodent subset of our genome-wide alignments (right phylogeny) and we highlighted the novel RHV genomes in turqoise. Lines connecting the two phylogenies represent an association between the rodent host species and their identified hepaciviruses. Blue lines correspond to individuals harbouring multiple hepaciviruses, while rodent species highlighted in a caramel colour represent the novel hosts found to be hepacivirus positive.