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. 2021 Jun 16;11:687629. doi: 10.3389/fonc.2021.687629

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Copyright © 2021 Naipauer, García Solá, Salyakina, Rosario, Williams, Coso, Abba, Mesri and Lacunza

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Host miRNAs expression. (A) Multidimensional scaling plot of the host miRNAs showing the distance of each sample from each other determined by their leading logFC. (B) Number of DE miRNAs in key biological comparisons that were detected by small RNA-sequencing analysis of: two KSHV (+) cells, two KSHV (−) cells, six KSHV (+) tumors, two KSHV (−) tumor cells and three KSHV (−) tumors. (C) Heat maps for fold change expression of host miRNAs based on analysis of small RNA sequencing data, only top 20 upregulated and top 20 downregulated DE host miRNAs are shown in each comparison.