Table 3.
Comparison of blood biochemical tests and serum electrolytes between mild patients and patients with severe COVID-19 infection.
| Normal range | Patients with mild disease (n = 30) | Patients with severe disease (n = 30) | p-value | F | |
|---|---|---|---|---|---|
| Liver related | |||||
| ALT (U/L) | 0.0–40.0 | 22.2 ± 5.8 | 28.37 ± 9.18 | <0.001 | 20.995 |
| AST (U/L) | 0.0–37.0 | 20.45 ± 3.33 | 46.06 ± 11.59 | <0.001 | 69.83 |
| ALP (U/L) | 45–125 | 62.48 ± 11.19 | 77.29 ± 14.93 | <0.001 | 9.462 |
| ALB (g/L) | 40–55 | 44.64 ± 3.51 | 28.61 ± 5.83 | <0.001 | 17.214 |
| TBIL (μmol/L) | 5.13–22.24 | 10.49 ± 2.47 | 13.01 ± 3.28 | <0.001 | 6.064 |
| DBIL (μmol/L) | 1.70–8.55 | 3.67 ± 0.81 | 5.33 ± 1.39 | <0.001 | 17.239 |
| Kidney related | |||||
| BUN (mmol/L) | 1.7–8.3 | 5.23 ± 1.48 | 6.32 ± 1.84 | 0.001 | 2.81 |
| Cr (μmol/L) | 36–132 | 58.75 ± 8.27 | 61.31 ± 7.95 | 0.109 | 0.073 |
| Heart related | |||||
| TnT (ng/mL) | 0–0.15 | 11.52 ± 5.68 | 13.69 ± 6.02 | 0.06 | 0.106 |
| CK (U/L) | 30–170 | 61.09 ± 19.52 | 94.69 ± 30.91 | <0.001 | 16.535 |
| LDH (U/L) | 90–245 | 163.93 ± 34.48 | 520.78 ± 121.38 | <0.001 | 53.866 |
| CK-MB (ng/mL) | 0–5 | 0.72 ± 0.12 | 1.88 ± 0.51 | <0.001 | 68.471 |
| proBNP (pg/mL) | 0–125 | 52.95 ± 22.66 | 399.22 ± 184 | <0.001 | 119.995 |
| Myo (ng/mL) | 0–70 | 26.77 ± 3.34 | 48.55 ± 7.7 | <0.001 | 25.186 |
| Serum electrolytes | |||||
| Na+ (mmol/L) | 135–155 | 147.16 ± 10.23 | 145.46 ± 8.47 | 0.359 | 4.488 |
| K+ (mmol/L) | 3.5–5.5 | 4.3 ± 0.63 | 4.09 ± 0.61 | 0.079 | 0.033 |
| Cl− (mmol/L) | 95–115 | 108.07 ± 4.94 | 107.8 ± 5.14 | 0.786 | 0.46 |
| Ca2+ (mmol/L) | 2.25–2.7 | 2.22 ± 0.07 | 1.91 ± 0.06 | <0.001 | 0.149 |