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. 2021 Apr 29;35(9):4988–5006. doi: 10.1002/ptr.7131

TABLE 1.

Inhibitory activities of flavonoids 37, 39–41 against SARS‐CoV 3CLpro

Flavonoid Activity

Quercetin‐3‐O‐β‐galactoside

(37)

SARS‐CoV 3CLpro

Inhibitor

IC50 = 42.8 μM

Quercetin‐3‐O‐β‐fucoside

(39)

SARS‐CoV 3CLpro

Inhibitor

IC50 = 24.1 μM

Quercetin‐3‐O‐β‐arabinoside

(40)

SARS‐CoV 3CLpro

Protease inhibitor

IC50 = 31.6 μM

Quercetin‐3‐O‐β‐glucoside

(41)

SARS‐CoV 3CLpro

Protease inhibitor

IC50 = 48.8 μM