TABLE 4.
Nucleotide polymorphisms identified in the sequenced SARS‐CoV‐2 strains. Numbering of nucleotide positions refers to the ‘Wuhan‐Hu‐1’ reference isolate. Amino‐acid substitutions refer to amino‐acid positions on the respective protein of the reference isolate
| Nucleotide position | ‘Wuhan‐Hu−1’ reference | Nucleotide change | Amino‐acid substitution | ORF/Protein |
|---|---|---|---|---|
| 241 | C | T | – | – |
| 2091 | C | T | T429I | ORF1a/NSP2 |
| 3037 | C | T | – | ORF1a/NSP3 |
| 3117 | C | T | T133I | |
| 10507 | C | T | – | ORF1a |
| 14408 a | C | T | P323L | ORF1b/NSP12 |
| 19839 | T | C | – | ORF1b |
| 23403 | A | G | D614G | S |
| 24544 b | T | C | – | |
| 24872 | C | T | V1104L | |
| 25448 | A | G | E19G | ORF3a |
| 26951 | C | T | – | M |
| 27798 | C | T | A15S | ORF7b |
| 28881 | G | A | R203K | N |
| 28882 | G | A | ||
| 28883 | G | C | ||
| 28884 | G | T | G204L |
a
Nucleotide change not verified in the faecal swab of C2 due to reduced depth.
b
Nucleotide change only in the oropharyngeal swab of C3