Table 5.

Association of hospital, age category, sex, address, initial BI category, and treatment extension, with treatment default.

	Crude rate ratio		0–6 mos follow-up (n = 902)		>6 mos follow-up (n = 677)
	Crude rate ratio (95% CI)	p-value	Adjusteda Hazard Ratio (95% CI)	p-value	Adjustedb Hazard Ratio (95% CI)	p- value
Hospital
A	1 (baseline)		1 (baseline)		1 (baseline)
B	0.88 (0.60–1.28)	0.49	(excluded)		2.80 (1.08–7.30)	0.04
C	1.15 (0.89–1.48)	0.28	1.02 (0.75–1.38)	0.91	1.56 (0.94–2.58	0.08
Age Group
15–29	1 (baseline)		1 (baseline)		1 (baseline)
30–44	0.79 (0.63–1.01)	0.06	0.72 (0.53–0.99)	0.04	1.00c (0.98–1.01)	0.79
45+	0.88 (0.68–1.13)	0.30	0.94 (0.68–1.30)	0.71
Sex
Male	1 (baseline)		1 (baseline)		1 (baseline)
Female	0.96 (0.76–1.21)	0.74	0.90 (0.66–1.23)	0.52	0.84 (0.52–1.35)	0.46
Address
Within Metro Manila	1 (baseline)		1 (baseline)		1 (baseline)
Outside Metro Manila	1.08 (0.88–1.32)	0.49	1.02 (0.78–1.34)	0.89	0.94 (0.63–1.40)	0.78
Initial BI
0.00	1 (baseline)		1 (baseline)		1 (baseline)
0.01–3.99	1.40 (0.97–2.00)	0.07	1.02c (0.95–1.10)	0.57	1.15c (1.03–1.29)	0.01
4.00+	1.30 (0.90–1.86)	0.16
Treatment extension
Not extended	1 (baseline)		1 (baseline)		1 (baseline)
Extended	0.17 (0.12–0.25)	<0.01	(excluded)		0.19 (0.10–0.36)	<0.01

^aAdjusted for Hospital (but excluding Hospital B), Age Group, Sex, Address, and Initial BI.

^bAdjusted for Hospital, Age Group, Sex, Address, Initial BI, and Treatment Extension.

^cCommon linear effect.