Table 1.

Cross-validated differentially expressed genes in HUAEC and HUVEC

DEG	GPL570 library	GSE131681	GSE128382	Average fold-change
HEY2	−20.68	−9.19	−12.27	−13.26
GJA5	−47.11	−6.70	−4.48	−11.22
XG	−17.26	−7.63	−8.72	−10.47
SLITRK4	−11.49	−4.70	−4.00	−6.00
FST	−11.19	−5.24	−3.58	−5.94
RASGRF2	−5.79	−5.93	−5.86	−5.86
PTGS1	2.10	7.50	8.79	5.17
ALDH1A2	1.76	7.15	9.08	4.85
FAM174B	3.50	5.20	5.24	4.57
MAP9	−5.80	−4.65	−3.47	−4.54
LHX6	1.92	4.41	10.55	4.47
SLC46A3	−8.16	−2.64	−4.03	−4.43
ADAMTS18	1.72	7.04	7.00	4.39
ZNF462	3.37	5.09	3.90	4.06
VGLL3	−3.47	−4.57	−3.97	−3.98
RBP1	3.03	4.75	4.28	3.95
CECR2	−7.33	−3.25	−2.56	−3.93
MOCOS	4.22	−2.99	−4.37	−3.81
NR2F2	3.09	3.66	4.80	3.79
TMEM163	−2.48	−3.12	−6.88	−3.76
DNM3OS	4.89	4.80	2.21	3.73
ITGA4	−3.74	−3.27	−4.10	−3.69
SHISA3	−9.15	−3.86	−1.39	−3.66
AR	1.73	5.86	4.77	3.64
MYRIP	6.69	4.29	1.65	3.62
ATP8A1	−5.79	−2.68	−2.91	−3.56
EEF1A2	1.90	5.56	4.19	3.54
ANK3	−4.44	−3.80	−2.45	−3.46
PDE2A	3.80	3.65	2.96	3.45
EPDR1	−3.96	−3.72	−2.73	−3.43
SFRP1	3.16	4.15	3.07	3.43
SLC45A4	−3.80	−3.08	−3.25	−3.36
AUTS2	3.37	4.49	2.35	3.29
FAM107A	−2.99	−3.13	−3.72	−3.26
CXADR	−3.01	−3.25	−3.49	−3.24
HSPB8	3.12	2.92	3.41	3.14
CD44	−2.77	−4.01	−2.78	−3.14
MAMDC2	−4.69	−4.25	−1.51	−3.11
TNFSF15	1.65	3.97	4.55	3.10
PLXNA4	1.93	2.59	5.23	2.97
SLIT2	−4.99	−3.20	−1.48	−2.87
CLU	2.50	3.09	3.01	2.86
FAT1	−2.43	−3.15	−2.89	−2.81
ANTXR1	−3.15	−3.01	−2.29	−2.79
SORT1	−3.65	−2.27	−2.52	−2.75
HIC1	2.27	3.51	2.50	2.71
TSPAN11	2.38	3.16	2.54	2.67
CPXM1	1.87	2.45	3.77	2.58
CAMK2N1	2.37	4.40	1.58	2.54
PDZD2	−3.05	−2.82	−1.87	−2.52
CUBN	−3.58	−2.77	−1.55	−2.49
ITGA1	−1.90	−2.81	−2.59	−2.40
UCP2	1.57	4.23	2.07	2.40
DOK5	1.73	3.93	1.82	2.31
CDC42EP5	1.89	2.96	1.96	2.22
FBP1	−1.62	−3.18	−2.09	−2.21
KLRG1	−1.61	−2.82	−2.36	−2.21
KALRN	1.58	2.82	2.32	2.18
SPHK1	1.86	2.93	1.77	2.13
NRP2	1.68	2.27	2.13	2.01
KANK3	2.47	3.30	0.99	2.01
LGR4	−2.16	−3.31	−1.11	−1.99
INHBA	−3.63	−2.94	−0.73	−1.98
PRR5	1.51	3.70	1.38	1.98
ASAP3	1.61	3.06	1.50	1.95
PALD1	3.01	2.34	1.04	1.94
PTGIS	−2.96	2.55	0.97	−1.94
SORBS2	−3.10	−1.94	−1.14	−1.90
LRP5	2.49	2.82	0.95	1.88
PDE3A	−2.35	−2.20	−1.29	−1.88
ADAMTS7	1.85	2.76	1.30	1.88
TRPV4	1.59	2.38	1.68	1.85
SLCO3A1	−2.56	−1.95	−1.24	−1.84
TUSC3	−3.12	−2.59	−0.65	−1.74
GNA14	−1.5	−2.54	−1.28	−1.71
CAPG	1.94	2.25	1.02	1.64
MMP15	1.54	2.26	1.15	1.59
SLC6A8	1.57	2.23	1.09	1.56
LY75	−1.51	−2.04	−1.21	−1.55
MAP1S	2.24	2.61	0.57	1.49
UBTD1	1.73	2.74	0.69	1.48
WFS1	1.58	2.41	0.64	1.35
MDK	1.73	2.07	0.54	1.25
SH3GL1	1.86	2.07	0.49	1.24

Values expressed as log₍₂₎ fold−change in HUVEC relative to HUAEC. Average fold−change calculated as the geometric average of changes in each dataset.