Table 3.

Levels of Growth Factors.

Growth Factors	Group 1	Group 2	Group 3	P
TGF-β (µg/ml)	Min-Max Mean ± SD
Before procedure	26.8–152.4	22.7–81.4	16.4–108.3	NS
	55.7 ± 43.6	38.4 ± 18.3	42.5 ± 22.9
Day 1	20.7–35.6	22.1–80.5	24.5–403.2	<.05
	26.9 ± 4.4	38.4 ± 18.4	84.9 ± 48.9
Day 4	24.5–33.5	21.5–79.7	25.9–272.1	<.05
	28.5 ± 3.2	37.2 ± 17.9	86 ± 81.5
Day 7	24.8–32.6	21.5–80.1	15.7–281.4	<.05
	29 ± 2.6	38.2 ± 11.9	89.2 ± 88.9
VEGF (pg/ml)
Before procedure	1306–3813	1150–3796	1496–3528	NS
	2797 ± 716.1	2263 ± 999.4	2842 ± 660.2
Day 1	1576–3748	1470–3788	2024–4679	P < .05
	2703 ± 685.9	2270 ± 1006.9	3222 ± 1048
Day 4	1254–3625	1204–3958	2170–5124	P < .05
	2524 ± 787.3	2373 ± 938.5	3138 ± 963.5
Day 7	1514–3152	1100–3854	1506.4–5241.6	P < .05
	2300 ± 560.2	2314 ± 892.9	3333 ± 1060
KGF (ng/ml)
Before procedure	138.3–172.3	101.1–591.2	130.4–473.9	NS
	155.1 ± 11	194.8 ± 140.6	218.4 ± 111.7
Day 1	142.8–182.4	111.5–595.3	106.5–584.6	NS
	161.8 ± 11.8	196.8 ± 141.7	216 ± 147.2
Day 4	147.4–180.5	107.5–497	132.6–397.6	NS
	165.7 ± 9.9	197.2 ± 141.6	206.1 ± 81.5
Day 7	149–178.5	111.4–597.9	157.7–502.2	P < .05
	164.8 ± 9	196.2 ± 142	228.2 ± 73.4
NGF (ng/ml)
Before procedure	1.3–65	0.2–20.4	1.2–15.4	NS
	12.2 ± 19.1	8.5 ± 12.4	5.8 ± 5.4
Day 1	0.6–15.8	0.1–22.5	0.1–21.1	NS
	7.5 ± 5.2	8.4 ± 12	6.7 ± 6.6
Day 4	2–16.3	1–20.5	2.1–16.8	NS
	7.7 ± 5.3	8.3 ± 9.6	12.1 ± 5.5
Day 7	1.5–15.5	0.9–17.1	2.1–24.6	P < .05
	7.8 ± 4.8	8.4 ± 12.3	13.7 ± 6.7

P-values following comparison between control groups (Group1 and Group-2) and the study group (Group-3). All values are given as minimum, maximum and mean, NS: not significant, SD: standart deviation.