Table 2.

Tryptophan metabolites in maternal serum, placenta, fetal plasma and brain following pCpG-MuIl17a transfer at E18.5.

	3-HK	3-HAA	AA
Maternal serum (nM)
Control	56.7 ± 9.14	70.7 ± 20.2	251.7 ± 24.7
MIA	72.1 ± 7.42	135.4 ± 23.9	165.0 ± 21.4*
Placenta (fmoL/mg tissue)
Control	47.1 ± 11.0	19.2 ± 4.14	257.6 ± 29.1
MIA	36.5 ± 2.57	17.0 ± 0.59	103.9 ± 10.4***
Fetal plasma (nM)
Control	39.1 ± 3.81	50.8 ± 7.86	309.2 ± 108.5
MIA	74.2 ± 8.81*	453.3 ± 32.3****	245.5 ± 37.0
Fetal brain (fmoL/mg tissue)
Subpallium
Control	117.5 ± 17.8	7.8 ± 0.66	24.7 ± 3.87
MIA	108.4 ± 7.68	9.4 ± 1.18	29.8 ± 3.21
Pallium
Control	81.3 ± 10.9	10.3 ± 1.26	19.6 ± 1.99
MIA	80.0 ± 9.51	10.1 ± 0.93	33.5 ± 5.87

Data are presented as means ± standard error of the mean (SEM).

^*P < .05, ***P < .001, ****P < .0001 vs control.