. 2021 Jun 28;13:17588359211022886. doi: 10.1177/17588359211022886

Table 3.

Comparison of predicted efficacy between prognostic nomogram and other prognostic biomarkers in stage I–III and IV CRC patients.

Stage	Outcome	Variants	12-month survival	24-month survival	36-month survival
			AUROC (95% CI)	AUROC (95% CI)	AUROC (95% CI)	C-index (95% CI)
I–III	RFS	Nomogram (FPR)	0.790 (0.761–0.823)	0.784 (0.755–0.830)	0.791 (0.756–0.839)	0.760 (0.735–0.785)
		Nomogram (non-FPR)	0.762 (0.732–0.804)^*	0.753 (0.714–0.806)^*	0.760 (0.722–0.805)^*	0.726 (0.693–0.747)^*
		FPR	0.664 (0.599–0.709)^**	0.646 (0.601–0.685)^**	0.653 (0.622–0.689)^**	0.634 (0.601–0.667)^**
		TNM	0.689 (0.644–7.35)^**	0.695 (0.633–0.746)^**	0.701 (0.660–0.742)^**	0.673 (0.636–0.700)^**
	OS	Nomogram (FPR)	0.772 (0.722–0.813)	0.803 (0.755–0.842)	0.795 (0.751–0.849)	0.780 (0.750–0.810)
		Nomogram (non-FPR)	0.717 (0.648–0.753)^**	0.745 (0.698–0.801)^*	0.744 (0.699–0.796)^*	0.730 (0.690–0.770)^*
		FPR	0.713 (0.655–0.752)^**	0.714 (0.644–0.766)^**	0.714 (0.668–0.742)^**	0.694 (0.652–0.736)^**
		TNM	0.652 (0.604–0.698)^**	0.676 (0.639–0.736)^**	0.672 (0.624–0.716)^**	0.660 (0.624–0.696)^**
IV	PFS	Nomogram (FPR)	0.737 (0.688–0.779)	0.773 (0.724–0.822)	0.777 (0.739–0.822)	0.671 (0.641–0.701)
		Nomogram (non-FPR)	0.644 (0.594–0.696)^**	0.670 (0.644–0.724)^**	0.693 (0.652–0.752)^**	0.615 (0.581–0.649)^**
		FPR	0.695 (0.658–0.762)^*	0.720 (0.639–0.762)^*	0.714 (0.659–0.748)^*	0.632 (0.605–0.659)^*
	OS	Nomogram (FPR)	0.779 (0.739–0.812)	0.794 (0.733–0.845)	0.821 (0.766–0.853)	0.718 (0.6935–0.743)
		Nomogram (non-FPR)	0.694 (0.638–0.751)^**	0.719 (0.647–0.751)^**	0.741 (0.701–0.749)^*	0.678 (0.650–0.705)^*
		FPR	0.674 (0.630–0.712)^**	0.690 (0.633–0.740)^**	0.723 (0.677–0.765)^**	0.629 (0.605–0.654)^**