Appendix H.

Sensitivity analyses IPTW-adjusted overall and RCC-specific survival at 1, 3, and 5 years, by treatment type in histologically-confirmed patients

	PA % (95% CI)	PN % (95% CI)	PA % (95% CI)	RN % (95% CI)
	RSS
1-year	99 (98–100)	99 (99–100)	99 (98–99)	99 (98–99)
3-year	97 (96–99)	99 (98–99)	97 (95–98)	97 (96–98)
5-year	94 (92–98)	98 (96–99)	94 (92–97)	94 (93–96)
OS
1-year	95 (94–97)	98 (97–98)	94 (92–95)	95 (94–96)
3-year	88 (85–90)	94 (93–95)	82 (80–85)	86 (85–88)
5-year	75 (71–79)	87 (85–89)	69 (66–73)	76 (74–78)

Notes:

-First two columns give survival probabilities for PA-PN matched cohorts; second two columns give survival probabilities for PA-RN matched cohorts.

-Survival probabilities generated from an Inverse Probability of Treatment-Weighted (IPTW) Cox model with a time-dependent treatment variable

-Results are essentially the same as those from primary analysis

-RCC, renal cell carcinoma; RSS, RCC-specific survival; OS, overall survival; PA, percutaneous ablation; PN, partial nephrectomy; RN, radical nephrectomy