Table 2.
Multinomial adjusted OR and 95% CIs associated with Hb <10 g/dL and >12 g/dL ERBP recommended target range throughout 25 431 consecutive patients visits
| Covariates | OR (95% CI) |
|
|---|---|---|
| Hb <10 g/dL | Hb >12 g/dL | |
| Age <65 years | Reference | Reference |
| Age 65–75 years | 0.88 (0.76–1.02) | 1.13 (1.04–1.23) |
| Age ≥75 years | 0.85 (0.74–0.98) | 0.98 (0.90–1.06) |
| Men | 1.23 (1.11–1.37) | 1.22 (1.15–1.30) |
| BMI <18.5 kg/m2 | Reference | Reference |
| BMI 18.5–25 kg/m2 | 0.97 (0.68–1.39) | 1.00 (0.81–1.24) |
| BMI ≥25 kg/m2 | 0.86 (0.77–0.97) | 0.99 (0.93–1.06) |
| CKD Stage G5 | Reference | Reference |
| CKD Stage G4 | 0.80 (0.71–0.91) | 1.34 (1.24–1.44) |
| CKD Stage G3b | 0.59 (0.47–0.75) | 1.85 (1.66–2.06) |
| Glomerulonephritis | Reference | Reference |
| Pyelonephritis | 1.32 (0.89–1.95) | 1.34 (1.10–1.62) |
| Diabetic nephropathy | 1.29 (1.03–1.63) | 0.75 (0.66–0.84) |
| Polycystic kidney disease | 1.49 (1.12–1.98) | 0.77 (0.66–0.90) |
| Nephrosclerosis | 1.52 (1.22–1.89) | 0.82 (0.73–0.92) |
| Other aetiology | 1.24 (0.996–1.54) | 0.85 (0.76–0.95) |
| Unknown aetiology | 1.38 (1.09–1.76) | 0.88 (0.78–0.996) |
| Kidney transplanted | 0.78 (0.39–1.59) | 1.83 (1.51–2.22) |
| Diabetes mellitus | 1.08 (0.93–1.25) | 1.02 (0.94–1.10) |
| Hypertension | 0.96 (0.81–1.15) | 1.05 (0.96–1.16) |
| CVD | 1.06 (0.95–1.20) | 0.97 (0.91–1.04) |
| Recent transfusion | 1.26 (1.10–1.45) | 0.96 (0.88–1.05) |
| Recent bleeding | 1.20 (1.05–1.37) | 1.02 (0.95–1.09) |
| Iron medication use | 0.96 (0.87–1.07) | 1.06 (1.002–1.13) |
| Non-use of ESA | Reference | Reference |
| ESA <3600 IU/week | 0.72 (0.63–0.83) | 0.87 (0.81–0.94) |
| ESA 3600–6400 IU/week | 0.95 (0.82–1.10) | 1.18 (1.08–1.29) |
| ESA ≥6400 IU/week | 1.07 (0.91–1.25) | 1.35 (1.21–1.50) |
| Statin | 0.86 (0.77–0.96) | 1.04 (0.98–1.11) |
| Sodium bicarbonate | 0.85 (0.76–0.95) | 0.99 (0.93–1.06) |
| hsCRP <5 mg/dL | Reference | Reference |
| hsCRP ≥5 mg/dL | 1.16 (1.04–1.30) | 0.91 (0.86–0.97) |
| Ca2+ (mmol/L) low tertile | 1.36 (1.20–1.54) | 0.82 (0.76–0.88) |
| Ca2+ (mmol/L) mid tertile | Reference | Reference |
| Ca2+ (mmol/L) high tertile | 0.81 (0.69–0.94) | 1.21 (1.13–1.30) |
| PO4− (mmol/L) low tertile | 0.88 (0.76–1.02) | 1.27 (1.19–1.37) |
| PO4− (mmol/L) mid tertile | Reference | Reference |
| PO4− (mmol/L) high tertile | 1.33 (1.17–1.51) | 0.90 (0.83–0.98) |
| PTH (ng/L) low tertile | 1.07 (0.93–1.24) | 1.00 (0.93–1.08) |
| PTH (ng/L) mid tertile | Reference | Reference |
| PTH (ng/L) high tertile | 1.11 (0.98–1.26) | 0.99 (0.92–1.07) |
| Albumin (per g/dL higher) | 0.93 (0.92–0.94) | 1.05 (1.04–1.05) |
| Previous Hb (per g/dL higher) | 0.97 (0.97–0.98) | 1.05 (1.05–1.06) |
Bold text indicates statistically significant higher or lower odds. Ca2+, calcium; PO4−, phosphate; PTH, parathyroid hormone.