Figure 4.
CB2R deficiency enhances neurogenetic damage in the hippocampus of adult mice exposed to Iso. (A) Representative images of immunostaining for BrdU (positive brown staining indicated with blue arrows; black scale bar, 200 µm; red scale bar in magnified window, 20 µm). (B) Quantification of the hippocampal BrdU+ cells. Values are expressed as the mean ± standard error of the mean (n=6) and analyzed using two-way ANOVA. ***P<0.001 and #P<0.05. BrdU, 5-bromodeoxyuridine; CB2R, cannabinoid receptor 2; WT, wild-type; KO, knockout; Iso, isoflurane; DG, dentate gyrus.
