Table 1. Baseline characteristics.
Variables | Total | ACS | Stable CAD | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
MAR < 0.014 (n=2220) | MAR ≥ 0.014 (n=1119) | χ2 or t | P-value | MAR < 0.014 (n=1698) | MAR ≥ 0.014 (n=849) | χ2 or t | P-value | MAR < 0.014 (n=522) | MAR ≥ 0.014 (n=270) | χ2 or t | P-value | |
Age, years | 62.74 ± 10.47 | 64.37 ± 10.92 | −4.189 | <0.001 | 62.81 ± 10.36 | 64.75 ± 10.50 | −4.436 | <0.001 | 62.52 ± 10.80 | 63.18 ± 12.07 | −0.758 | 0.449 |
Gender (male), n (%) | 1441 (64.9) | 858 (76.7) | 48.024 | <0.001 | 1105 (65.1) | 651 (76.7) | 35.582 | <0.001 | 336 (64.4) | 207 (76.7) | 12.488 | <0.001 |
Smoking, n (%) | 620 (27.9) | 397 (35.5) | 20.023 | <0.001 | 480 (28.3) | 294 (34.6) | 10.824 | 0.001 | 140 (26.8) | 103 (38.1) | 10.738 | 0.001 |
Alcohol drinking, n (%) | 340 (15.3) | 200 (17.9) | 3.590 | 0.058 | 264 (15.5) | 149 (17.6) | 1.670 | 0.196 | 76 (14.6) | 51 (18.9) | 2.477 | 0.115 |
Diabetes, n (%) | 514 (23.2) | 273 (24.4) | 0.639 | 0.424 | 400 (23.6) | 210 (24.7) | 0.431 | 0.511 | 114 (21.8) | 63 (23.3) | 0.229 | 0.632 |
Hypertension, n (%) | 1242 (55.9) | 614 (54.9) | 0.349 | 0.555 | 946 (55.7) | 478 (56.3) | 0.080 | 0.778 | 296 (56.7) | 136 (50.4) | 2.880 | 0.090 |
Heart rate, rpm | 74.10 ± 20.38 | 75.55 ± 11.92 | −2.150 | 0.032 | 74.12 ± 20.59 | 75.68 ± 12.05 | −1.863 | 0.063 | 74.10 ± 10.32 | 75.13 ± 11.52 | −1.267 | 0.205 |
Monocytes, 109/l | 0.43 ± 0.10 | 0.77 ± 0.41 | −27.04 | <0.001 | 0.43 ± 0.10 | 0.77 ± 0.39 | −33.322 | <0.001 | 0.44 ± 0.09 | 0.78 ± 0.47 | −11.829 | <0.001 |
Alb, g/l | 41.65 ± 4.11 | 39.14 ± 4.92 | 14.70 | <0.001 | 41.64 ± 4.27 | 39.25 ± 4.71 | 12.882 | <0.001 | 41.70 ± 3.55 | 38.82 ± 5.52 | 14.707 | <0.001 |
Cr, μmol/l | 70.39 ± 24.69 | 77.69 ± 51.08 | −5.547 | <0.001 | 70.42 ± 23.05 | 76.02 ± 29.67 | −5.218 | <0.001 | 70.29 ± 29.46 | 82.97 ± 89.76 | −2.246 | 0.025 |
UA, mmol/l | 294.81 ± 82.33 | 307.50 ± 91.96 | −4.017 | <0.001 | 294.83 ± 81.99 | 304.73 ± 93.49 | −2.609 | 0.006 | 294.74 ± 83.49 | 316.27 ± 86.50 | −3.371 | 0.001 |
TG, mmol/l | 1.69 ± 1.17 | 1.62 ± 1.02 | 1.778 | 0.075 | 1.68 ± 1.16 | 1.59 ± 0.95 | 1.805 | 0.071 | 1.74 ± 1.19 | 1.69 ± 1.22 | 0.482 | 0.630 |
TC, mmol/l | 3.92 ± 1.03 | 3.86 ± 1.01 | 1.608 | 0.108 | 3.93 ± 1.03 | 3.86 ± 1.02 | 1.513 | 0.130 | 3.91 ± 1.03 | 3.87 ± 1.01 | 0.582 | 0.559 |
LDL-C, mmol/l | 2.40 ± 0.84 | 2.40 ± 0.85 | 0.184 | 0.854 | 2.40 ± 0.85 | 2.40 ± 0.85 | 0.053 | 0.958 | 2.39 ± 0.81 | 2.37 ± 0.83 | 0.287 | 0.774 |
HDL-C, mmol/l | 1.06 ± 0.30 | 1.00 ± 0.27 | 4.621 | <0.001 | 1.05 ± 0.31 | 1.00 ± 0.26 | 4.192 | <0.001 | 1.06 ± 0.29 | 1.02 ± 0.29 | 1.986 | 0.047 |
CCB, n (%) | 409 (18.4) | 171 (15.3) | 5.117 | 0.024 | 296 (17.4) | 133 (15.7) | 1.261 | 0.261 | 113 (21.6) | 38 (14.1) | 6.615 | 0.010 |
β-blocker, n (%) | 1134 (51.1) | 553 (49.4) | 0.822 | 0.365 | 854 (50.3) | 422 (49.7) | 0.079 | 0.779 | 280 (53.6) | 131 (48.5) | 1.870 | 0.172 |
ACEI or ARB, n (%) | 633 (28.5) | 304 (27.2) | 0.668 | 0.414 | 456 (26.9) | 225 (26.5) | 0.036 | 0.849 | 177 (33.9) | 79 (29.3) | 1.758 | 0.185 |
Statin, n (%) | 1804 (81.3) | 856 (76.5) | 10.425 | 0.001 | 1379 (81.2) | 647 (76.2) | 8.717 | 0.003 | 425 (81.4) | 209 (77.4) | 1.792 | 0.181 |
Aspirin, n (%) | 1878 (84.6) | 896 (80.1) | 10.827 | 0.001 | 1425 (83.9) | 677 (79.7) | 6.863 | 0.009 | 453 (86.8) | 219 (81.1) | 4.451 | 0.035 |
Clopidogrel, n (%) | 529 (23.8) | 281 (25.1) | 0.666 | 0.414 | 405 (23.9) | 219 (25.8) | 1.156 | 0.282 | 124 (23.8) | 62 (23.0) | 0.062 | 0.803 |
Abbreviations: LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride. The boldfaced values indicate P<0.05.