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. Author manuscript; available in PMC: 2021 Jun 30.
Published in final edited form as: Eur Respir J. 2020 Apr 16;55(4):1901761. doi: 10.1183/13993003.01761-2019

FIGURE 4.

FIGURE 4

Comparison of interleukin (IL)-6 levels in conditioned media from a) smooth muscle cells (SMCs) and endothelial cells (EC) from transplanted pulmonary arterial hypertension (PAH) subjects and non-transplanted donor controls (p<0.0001 for SMC-PAH versus EC-PAH); b) SMCs in controls and PAH subtypes; and c) ECs in controls and PAH subtypes. Comparison of IL-6 gene expression levels by fragments per kilobase of exon model per million reads mapped (FPKM) between d) SMCs and ECs from PAH subjects and controls (p<0.0001 for SMC-PAH versus EC-PAH); e) SMCs in controls and PAH subtypes; and f) ECs in controls and PAH subtypes. APAH: disease-associated PAH subtypes; IPAH: idiopathic PAH; FPAH: familial PAH.